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![Discovery of Clinical Candidate N-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915): A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A ...](https://pubs.acs.org/cms/10.1021/acs.jmedchem.7b00807/asset/images/large/jm-2017-00807f_0023.jpeg "Discovery of Clinical Candidate N-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915): A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A ...")
Discovery of Clinical Candidate N-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915): A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A ...
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![Image 14 of New York journal and advertiser (New York [N.Y.]), April 19, 1899 | Library of Congress](http://tile.loc.gov/image-services/iiif/service:sgp:sgpbatches:batch_dlc_chrystie_ver02:data:sn83030180:print2468:1899041901:0392/full/pct:6.25/0/default.jpg "Image 14 of New York journal and advertiser (New York [N.Y.]), April 19, 1899 | Library of Congress")
Image 14 of New York journal and advertiser (New York [N.Y.]), April 19, 1899 | Library of Congress
US20130281435A1 - Therapeutic agent for irritable bowel syndrome - Google Patents
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